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ROLE OF HEALTHCARE PROFESSIONALS IN INCREASING AWARENESS ON INFECTIOUS DISEASE – TYPHOID

Aleena Chishty, Lubna Rehmat, Hassaan Bukhari, Nahin Haseen, Arifa Noor

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Karachi University Pharmacy Science Club, Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi, Karachi, Pakistan


ROLE OF HEALTHCARE PROFESSIONALS IN INCREASING AWARENESS ON INFECTIOUS DISEASE – TYPHOID

Background

Typhoid caused by Salmonella Typhi, a gram –ve bacteria infects 21.6 mn people, killing 200,000 every year.

Healthcare professionals being the center of communities and reachable to masses; play a critical role in providing healthcare; and alongside, creating awareness in people regarding protection from infectious diseases, preventive measures, first aid to tackle the infection and long term solution based connections.

 

Introduction

Pakistan has the highest estimated incidence rate of typhoid fever (493.5 per 100,000 persons/year). physician is responsible for correct prescription of medicines, pharmacists are responsible to develop healthy combination of drugs that is efficacious with least side effects and nurses play a key role in preventing typhoid infection by offering advice on prevention.

In 2016, a multidrug-resistant Typhi strain that is resistant to ampicillin, chloramphenicol, and trimethoprim-sulfamethoxazole and additionally to ciprofloxacin and ceftriaxone was identified that are used as first and second line of therapies in patients hospitalized in Pakistan.

Clinical information from Pakistan indicates that third line therapies including azithromycin and meropenem are the most effective antibiotics for treating S typhi. For prevention two vaccines against typhoid are currently available in Pakistan, first one is a single dose of injectable Vi polysaccharide vaccine and second is a single dose typhoid conjugate vaccine.

 

Role of HealthCare Professionals in Treating Typhoid in the Past

The drinking water chlorination concept made a significant impact on the number of individuals affected by the disease, which was invented by John L. Leal; a Physician and sanitary adviser to drinking water companies.

Sidney Katz, a geriatrician and health services researcher proposed the concept of Activities of daily living (ADLs) in 1950, i.e. measurement of functional status of patients. This concept is widely used by the nursing staff and healthcare professions today.

 

Objectives

The Physicians are responsible to negate fatalistic laymen views in regard to typhoid’s occurrence and convey masses the necessary preventive developments regarding the lifestyles, usage of first aid medications, demotivate wrong use of empirical therapies resulting in its resistance by organism. The Pharmacists are responsible to develop healthy combination of drugs that is efficacious with least side effects and difficult to tackle by the infectious organism, preventing the disastrous developments by germs against humane health. Hence, our goal is:

·       To discuss about importance & role of these health care experts.

·       To study & aware about typhoid, and negate its misconceptions & misuses of medication in it; specifically in Pakistan.

·       To frame future policy adaptions by the health care experts to maximize their roles and utilization in awareness and decrement of diseases Treatment of Uncomplicated Typhoid Fever According to World Health Organization Guidelines.

 

Methodology

The method of analytical study of various articles stating about the development of typhoid’s management, was used & the historical and critical site descriptions were incorporated into the study.

The data and facts were also taken from conducted survey among common people.

 

Typhoid Awareness Survey Among Common People



Typhoid prevalence in major areas of Pakistan, as per IDSR weekly bulletin NIH Islamabad’s report in 2021


Treatment of Uncomplicated Typhoid Fever
According to World Health Organization Guidelines


Future Policy To Maximize The Role Of Pharmacists, Physicians, & Nurses

·       Awareness sessions by Marketing Pharmacists.

·       Physicians' medication awareness to patients.

·       Nursing trainings with ADL learning.

·       Budget increment for sponsorship.

·       Staff's regular typhoid checkup.

·       Free blood tests in slum areas.

·       Typhoid regimen consensus by Health care professionals and Researchers.

·       Physicians' guide to regimen completion.

·       Induction of qualified Retail Pharmacists at medical stores.

 

Conclusion

The health care sector is responsible to negate fatalistic laymen views in regard to typhoid’s occurrence and convey masses the necessary preventive developments regarding the lifestyles, usage of first aid medications, demotivate wrong use of empirical therapies resulting in its resistance by organism. Taking witnesses of obligations of health care professionals from the past, analyzing their contributions, negligence and researches and seeking for the betterments which can be made in future to deal effectively with the disease, is the purpose of this study.

 

References:

  1. https://www.who.int/teams/health-workforce/health-professions-networks
  2. Panzner U, Pak GD, Aaby P, Adu-Sarkodie Y, Ali M, Aseffa A, Baker S, Bjerregaard-Andersen M, Crump JA, Deerin J, Cruz Espinoza LM, Gasmelseed N, Heriniaina JN, Hertz JT, Im J, von Kalckreuth V, Keddy KH, Lankoande B, Løfberg S, Meyer CG, Oresto MM, Park JK, Park SE, Rakotozandrindrainy R, Sarpong N, Soura AB, Gassama Sow A, Tall A, Teferi M, Worku A, Yeshitela B, Wierzba TF, Marks F. Utilization of Healthcare in the Typhoid Fever Surveillance in Africa Program. Clin Infect Dis. 2016 Mar 15;62
  3. Crump JA, Luby SP, Mintz ED. The global burden of typhoid fever. Bull World Health Organ. 2004 May. 82(5):346-53.
  4. WHO: Background document: The diagnosis, treatment and prevention of typhoid fever. Geneva, World Health Organization Communicable Disease Surveillance and Response. WHO/V&B/03.07; 2003
  5. ZakiS. A., & KarandeS. (2011). Multidrug-resistant typhoid fever: a review. The Journal of Infection in Developing Countries, 5(05), 324-337.
  6. https://www.mmidsp.com/typhoid-management-guidelines-2019/

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